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1

Gene therapy for hemophilia

Marinee K. L. Chuah, Desire Collen, Thierry VandenDriessche

Journal:

The Journal of Gene Medicine

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

2

Involvement of Sp1 in basal and retinoic acid induced transcription of the human tissue-type plasminogen activator gene

Pascal Merchiers, Frank Bulens, Astrid De Vriese, Désiré Collen, Alexandra Belayew

Journal:

Year:

1999

Language:

english

File:

PDF, 258 KB

english, 1999

3

Coronary Thrombolysis with Tissue-Type Plasminogen Activator in Patients with Evolving Myocardial Infarction

Werf, Frans Van de, Ludbrook, Philip A., Bergmann, Steven R., Tiefenbrunn, Alan J., Fox, Keith A. A., Geest, Hilaire de, Verstraete, Marc, Collen, Desire, Sobel, Burton E.

Journal:

Boston Medical and Surgical Journal

Year:

1984

Language:

english

File:

PDF, 1.50 MB

english, 1984

4

Both u-PA inhibition and vitronectin binding by plasminogen activator inhibitor 1 regulate HT1080 fibrosarcoma cell metastasis

Michael Praus, Désiré Collen, Robert D. Gerard

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

5

Nonisotopic Quantitative Analysis of Protein–DNA Interactions at Equilibrium

Abderrafi M. Benotmane, Marc F. Hoylaerts, Désiré Collen, Alexandra Belayew

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997

6

Gene therapy for hemophilia: hopes and hurdles

Marinee K.L Chuah, Desire Collen, Thierry VandenDriessche

Journal:

Critical Reviews in Oncology/Hematology

Year:

1998

Language:

english

File:

PDF, 237 KB

english, 1998

7

Prostromelysin-1 (proMMP-3) stimulates plasminogen activation by tissue-type plasminogen activator

Begoña Arza, Marc F. Hoylaerts, Jordi Félez, Désiré Collen, H. Roger Lijnen

Journal:

Year:

2000

Language:

english

File:

PDF, 525 KB

english, 2000

8

Critical role of glutamic acid 202 in the enzymatic activity of stromelysin-1 (MMP-3)

Begoña Arza, Marc De Maeyer, Jordi Félez, Désiré Collen, H. Roger Lijnen

Journal:

Year:

2001

Language:

english

File:

PDF, 441 KB

english, 2001

9

Vascular development and disorders: Molecular analysis and pathogenic insights

Carmeliet, Peter, Collen, Desire

Journal:

Kidney International

Year:

1998

Language:

english

File:

PDF, 347 KB

english, 1998

10

Current clinical experience with staphylokinase in arterial thrombosis

Steven Vanderschueren, Désiré Collen, Frans Werf

Journal:

Journal of Thrombosis and Thrombolysis

Year:

1996

Language:

english

File:

PDF, 413 KB

english, 1996

11

The pathophysiological role of fibrinolysis inhibitors

Henri R. Lijnen, Désire Collen

Journal:

International Journal of Clinical & Laboratory Research

Year:

1984

Language:

english

File:

PDF, 412 KB

english, 1984

12

Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury

Zsolt Szelid, Peter Pokreisz, Xiaoshun Liu, Pieter Vermeersch, Glenn Marsboom, Hilde Gillijns, Marijke Pellens, Erik Verbeken, Frans Van de Werf, Desire Collen, Stefan P. Janssens

Journal:

Basic Research in Cardiology

Year:

2010

Language:

english

File:

PDF, 523 KB

english, 2010

13

A dose-finding clinical trial of staphylokinase SY162 in patients with long-term venous access catheter thrombotic occlusion

Peter Verhamme, Godelieve Goossens, Geert Maleux, Désiré Collen, Marguerite Stas

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2007

Language:

english

File:

PDF, 132 KB

english, 2007

14

The role of proteinases in angiogenesis, heart development, restenosis, atherosclerosis, myocardial ischemia, and stroke: Insights from genetic studies

Aernout Luttun, Mieke Dewerchin, Désiré Collen, Peter Carmeliet

Journal:

Current Atherosclerosis Reports

Year:

2000

Language:

english

File:

PDF, 432 KB

english, 2000

15

Insights in Vessel Development and Vascular Disorders Using Targeted Inactivation and Transfer of Vascular Endothelial Growth Factor, the Tissue Factor Receptor, and the Plasminogen System

PETER CARMELIET, LIEVE MOONS, M. DEWERCHIN, NIGEL MACKMAN, THOMAS LUTHER, GEORG BREIER, V. PLOPLIS, M. MÜLLER, A. NAGY, E. PLOW, R. GERARD, THOMAS EDGINGTON, W. RISAU, DÉSIRÉ COLLEN

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 984 KB

english, 1997

16

Molecular Basis of Angiogenesis: Role of VEGF and VE-Cadherin

PETER CARMELIET, DESIRE COLLEN

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

17

Molecular mechanism of physiological fibrinolysis

WIMAN, BJÖRN, COLLEN, DÉSIRÉ

Journal:

Year:

1978

File:

PDF, 235 KB

1978

18

10.1038/35017105

De Strooper, Bart, Herreman, An, Serneels, Lutgarde, Annaert, Wim, Collen, Desiré, Schoonjans, Luc

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

19

Physiological consequences of loss of plasminogen activator gene function in mice

Carmeliet, Peter, Schoonjans, Luc, Kieckens, Lena, Ream, Beverly, Degen, Jay, Bronson, Roderick, De Vos, Rita, van den Oord, Joost J., Collen, Désiré, Mulligan, Richard C.

Journal:

Year:

1994

File:

PDF, 914 KB

1994

20

10.1038/36862

Collen, Désiré, Rosen, Elliot D., Chan, Joyce C. Y., Idusogie, Esohe, Clotman, Frédéric, Vlasuk, George, Luther, Thomas, Jalbert, Louise R., Albrecht, Sybille, Zhong, Liang, Lissens, Ann, Schoonjans,

Journal:

Year:

1997

Language:

english

File:

PDF, 563 KB

english, 1997

21

10.1038/368666a0

Collen, Désiré, Rosen, Elliot D., Chan, Joyce C. Y., Idusogie, Esohe, Clotman, Frédéric, Vlasuk, George, Luther, Thomas, Jalbert, Louise R., Albrecht, Sybille, Zhong, Liang, Lissens, Ann, Schoonjans,

Journal:

Year:

1994

File:

PDF, 146 KB

1994

22

10.1038/84667

Angelillo-Scherrer, Anne, de Frutos, Pablo Garcia, Aparicio, Cristina, Melis, Els, Savi, Pierre, Lupu, Florea, Arnout, Jef, Dewerchin, Mieke, Hoylaerts, Marc F., Herbert, Jean-Marc, Collen, Désiré, Da

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 1.35 MB

english, 2001

23

High Yield Production and Purification of Recombinant Staphylokinase for Thrombolytic Therapy

Hartmann, Manfred, Gührs, Karl-Heinz, Birch-Hirschfeid, Eckhard, Pohl, Hans-Dieter, Vanderschueren, Steven, Werf, Frans Van de, Michoel, Armand, Collen, Désiré, Behnke, Detlev, Schlott, Bernhard

Journal:

Year:

1994

File:

PDF, 754 KB

1994

24

A mouse model for Zellweger syndrome

Baes, Myriam, Gressens, Pierre, Baumgart, Eveline, Carmeliet, Peter, Casteels, Minne, Fransen, Marc, Evrard, Philippe, Fahimi, Dariush, Declercq, Peter E., Collen, Désiré

Journal:

Nature Genetics

Year:

1997

File:

PDF, 1.63 MB

1997

25

Staphylokinase: a potent, uniquely fibrin-selective thrombolytic agent

Collen, Désiré

Journal:

Nature Medicine

Year:

1998

File:

PDF, 1.00 MB

1998

26

The interaction between components of the fibrinolytic system and GPIb/V/IX of platelets thrombus formation in mice

Hiroyuki Matsuno, Osamu Kozawa, Shigeru Ueshima, Osamu Matsuo, Désiré Collen, Toshihiko Uematsu

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 226 KB

english, 2000

27

Pluripotential rabbit embryonic stem (ES) cells are capable of forming overt coat color chimeras following injection into blastocysts

Luc Schoonjans, George M. Albright, Jai-Ling Li, Désiré Collen, Randall W. Moreadith

Journal:

Molecular Reproduction and Development

Year:

1996

Language:

english

File:

PDF, 1.99 MB

english, 1996

28

Efficient Lentiviral Transduction and Improved Engraftment of Human Bone Marrow Mesenchymal Cells

An Van Damme, Lieven Thorrez, Ling Ma, Herman Vandenburgh, Jeroen Eyckmans, Francesco Dell'Accio, Cosimo De Bari, Frank Luyten, David Lillicrap, Désiré Collen, Thierry VandenDriessche, Marinee K.L. Ch

Journal:

Year:

2006

Language:

english

File:

PDF, 890 KB

english, 2006

29

Sustained Endothelial Progenitor Cell Dysfunction After Chronic Hypoxia-Induced Pulmonary Hypertension

Glenn Marsboom, Peter Pokreisz, Olivier Gheysens, Pieter Vermeersch, Hilde Gillijns, Marijke Pellens, Xiaoshun Liu, Désiré Collen, Stefan Janssens

Journal:

Year:

2008

Language:

english

File:

PDF, 2.34 MB

english, 2008

30

Improved Generation of Germline-Competent Embryonic Stem Cell Lines from Inbred Mouse Strains

Luc Schoonjans, Veerle Kreemers, Sophie Danloy, Randall W. Moreadith, Yves Laroche, Désiré Collen

Journal:

Year:

2003

Language:

english

File:

PDF, 89 KB

english, 2003

31

Breaking the Species Barrier: Derivation of Germline-Competent Embryonic Stem Cells from Mus spretus × C57BL/6 Hybrids

Tino Hochepied, Luc Schoonjans, Jan Staelens, Veerle Kreemers, Sophie Danloy, Leen Puimège, Désiré Collen, Frans Van Roy, Claude Libert

Journal:

Year:

2004

Language:

english

File:

PDF, 937 KB

english, 2004

32

Efficiency of Onco-Retroviral and Lentiviral Gene Transfer into Primary Mouse and Human B-Lymphocytes Is Pseudotype Dependent

Janssens, Wim, Chuah, Marinee K.L., Naldini, Luigi, Follenzi, Antonia, Collen, Désiré, Saint-Remy, Jean-Marie, VandenDriessche, Thierry

Journal:

Human Gene Therapy

Year:

2003

Language:

english

File:

PDF, 1.10 MB

english, 2003

33

Acute coronary thrombolysis with recombinant human tissue-type plasminogen activator: Initial patency and influence of maintained infusion on reocclusion rate

Marc Verstraete, Alfred E.R. Arnold, Ronald W. Brower, Désiré Collen, David P. de Bono, Chris De Zwaan, Rainer Erbel, W.Stuart Hillis, R.John Lennane, Jacobus Lubsen, Detlef Mathey, Douglas S. Reid, W

Journal:

The American Journal of Cardiology

Year:

1987

Language:

english

File:

PDF, 961 KB

english, 1987

34

Coronary arterial thrombolysis with low-dose synergistic combinations of recombinant tissue-type plasminogen activator (rt-PA) and recombinant single-chain urokinase-type plasminogen activator (rscu-PA) for acute myocardial infarction

Désiré Collen, Frans Van De Werf

Journal:

The American Journal of Cardiology

Year:

1987

Language:

english

File:

PDF, 404 KB

english, 1987

35

Questions unresolved by the third international study of infarct survival

Burton E. Sobel, Désiré Collen

Journal:

The American Journal of Cardiology

Year:

1992

Language:

english

File:

PDF, 705 KB

english, 1992

36

Designing thrombolytic agents: Focus on safety and efficacy

Désiré Collen

Journal:

The American Journal of Cardiology

Year:

1992

Language:

english

File:

PDF, 1.29 MB

english, 1992

37

On the future of thrombolytic therapy for acute myocardial infarction

Désiré Collen, Henri Roger Lijnen

Journal:

The American Journal of Cardiology

Year:

1993

Language:

english

File:

PDF, 649 KB

english, 1993

38

Strokes, statistics and sophistry in trials of thrombolysis for acute myocardial infarction

Burton E. Sobel, Désiré Collen

Journal:

The American Journal of Cardiology

Year:

1993

Language:

english

File:

PDF, 522 KB

english, 1993

39

Reply

Burton E. Sobel, Desire Collen

Journal:

The American Journal of Cardiology

Year:

1993

Language:

english

File:

PDF, 449 KB

english, 1993

40

Physicochemical, immunochemical and functional comparison of human histidine-rich glycoprotein and autorosette inhibition factor

Henri R. Lijnen, Dennis B. Rylatt, Désiré Collen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1983

Language:

english

File:

PDF, 591 KB

english, 1983

41

On the molecular interactions between plasminogen-staphylokinase, α2-antiplasmin-formula> and fibrin

H. Roger Lijnen, Berthe Van Hoef, Osamu Matsuo, Désiré Collen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1992

Language:

english

File:

PDF, 434 KB

english, 1992

42

Dynamic structural and functional relationships in recombinant plasminogen activator inhibitor-1 (rPAI-1)

Douglas E. Vaughan, Paul J. Declerck, Thomas M. Reilly, Kyusung Park, Désiré Collen, Gerald D. Fasman

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1993

Language:

english

File:

PDF, 823 KB

english, 1993

43

Functional properties of recombinant staphylokinase variants obtained by site-specific mutagenesis of methionine-26

Bernard Schlott, Manfred Hartmann, Karl-Heinz Gührs, Eckehart Birch-Hirschfeld, Ariane Gase, Stephan Vettermann, Désiré Collen, Henri R. Lijnen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1994

Language:

english

File:

PDF, 744 KB

english, 1994

44

Role of the plasminogen/plasmin system in thrombosis, hemostasis, restenosis and atherosclerosis evaluation in transgenic animals

Peter Carmeliet, Désiré Collen

Journal:

Trends in Cardiovascular Medicine

Year:

1995

Language:

english

File:

PDF, 805 KB

english, 1995

45

Emerging treatments for thrombocytopenia: Increasing platelet production

Karen Peeters, Jean-Marie Stassen, Désiré Collen, Chris Van Geet, Kathleen Freson

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

46

Endothelium in hemostasis and thrombosis

Henri R. Lijnen, Désiré Collen

Journal:

Progress in Cardiovascular Diseases

Year:

1997

Language:

english

File:

PDF, 755 KB

english, 1997

47

Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-α, TNF-α converting enzyme and ADAMTS family members in murine fat territories

Gabor Voros, Erik Maquoi, Désiré Collen, H.Roger Lijnen

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2003

Language:

english

File:

PDF, 209 KB

english, 2003

48

Inactivation of the serpin α2-antiplasmin by stromelysin-1

H.Roger Lijnen, Berthe Van Hoef, Désiré Collen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2001

Language:

english

File:

PDF, 353 KB

english, 2001

49

Clinical development of PEGylated recombinant staphylokinase (PEG–Sak) for bolus thrombolytic treatment of patients with acute myocardial infarction

Randall W Moreadith, Désiré Collen

Journal:

Advanced Drug Delivery Reviews

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

50

1 Mechanisms of physiological fibrinolysis

H. Roger Lijnen, Desire Collen

Journal:

Baillière's Clinical Haematology

Year:

1995

Language:

english

File:

PDF, 1.21 MB

english, 1995

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